The aim of the research was to compare self-esteem and irrational beliefs in women candidates and non-candidates for hair mesotherapy, which was used after the event (causal-comparative) study method. The statistical population included women candidates and non-candidates for hair mesotherapy in spring In 1402, they visited Qazvin Skin and Hair Clinic. The sample consisted of 300 people who were selected through available sampling. To collect information, Rosenberg's self-esteem scale questionnaire and Jones-Ahvaz irrational beliefs test were used. The results showed that there is a statistically significant difference in the self-respect of women candidates and non-candidates for hair mesotherapy, and the level of self-respect in women candidates for hair mesotherapy is lower than that of women who are not candidates for hair mesotherapy, but the results show a significant difference in the irrational beliefs of candidate and non-candidate women. Doing hair mesotherapy did not show. (P>0.05).